RNU2-58P

Across TCGA pan-cancer cohorts, RNU2-58P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU2-58P data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RNU2-58P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU2-58P expression acts as an unfavorable survival marker, although some lineages such as UCS and ESCA show a favorable association.

COAD, KIRC, and UCS are the cancer types where RNU2-58P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	III,IV	0.385	0.610	<.001	93	view →
KIRC	DFS	Tertile	II,III,IV	0.482	0.725	.005	36	view →
UCS	OS	Median	II,III,IV	0.760	0.493	.016	22	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
LUSC	DFS	Quartile	III,IV	0.154	0.799	.001	18	view →
ESCA	OS	Tertile	III,IV	0.543	0.301	.028	9	view →
PCPG	DFS	Tertile	All	0.723	0.947	.002	9	view →
SKCM	DFS	Tertile	III,IV	0.186	0.276	.033	6	view →
UCEC	OS	Tertile	All	0.896	0.941	.015	6	view →
PAAD	OS	Tertile	II,III,IV	0.504	0.350	.044	3	view →
LUAD	OS	Tertile	All	0.526	0.308	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RNU2-58P–COAD (DFS)

Open the COAD breakdown →