RNU2-46P

Across TCGA pan-cancer cohorts, RNU2-46P RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated RNU2-46P data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RNU2-46P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU2-46P expression acts as an unfavorable survival marker, although some lineages such as GBM and KIRP show a favorable association.

COAD, READ, and LUSC are the cancer types where RNU2-46P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	III,IV	0.169	0.564	.006	96	view →
READ	DFS	Tertile	III,IV	0.349	0.776	<.001	48	view →
LUSC	OS	Tertile	II,III,IV	0.643	0.766	.011	45	view →
LIHC	DFS	Tertile	All	0.328	0.556	.002	36	view →
GBM	OS	Tertile	All	0.632	0.374	.001	27	view →
TGCT	OS	Tertile	II,III,IV	0.670	1.000	.005	18	view →
SARC	OS	Tertile	All	0.592	0.790	.008	15	view →
ESCA	DFS	Median	IV	0.216	0.542	.021	12	view →
STAD	DFS	Quartile	IV	0.104	0.649	.007	12	view →
KIRP	DFS	Tertile	All	1.000	0.683	.027	12	view →
LGG	OS	Median	All	0.303	0.537	.004	10	view →
SKCM	DFS	Tertile	All	0.296	0.184	.016	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

RNU2-46P–COAD (OS)

Open the COAD breakdown →