RNU2-46P

Across TCGA pan-cancer cohorts, RNU2-46P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNU2-46P’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where RNU2-46P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU2-46P is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

STAD, THCA, and KICH are the cancer types where RNU2-46P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU2-46P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	Male	All	+0.348	.004	4	view →
THCA	All	All	−0.257	.001	3	view →
KICH	Male	All	−0.312	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RNU2-46P–STAD

Open the STAD breakdown →