RNU2-35P

Across TCGA pan-cancer cohorts, RNU2-35P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU2-35P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNU2-35P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU2-35P expression acts as an unfavorable survival marker, although some lineages such as BRCA and LUSC show a favorable association.

KICH, ACC, and DLBC are the cancer types where RNU2-35P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	III,IV	0.155	0.818	<.001	123	view →
ACC	OS	Tertile	All	0.354	0.839	<.001	120	view →
DLBC	OS	Tertile	II,III,IV	0.096	0.865	<.001	45	view →
KIRC	OS	Tertile	All	0.732	0.822	.001	45	view →
READ	DFS	Tertile	III,IV	0.380	0.793	<.001	36	view →
STAD	DFS	Quartile	II,III,IV	0.401	0.757	<.001	24	view →
PCPG	OS	Tertile	All	0.516	0.947	.009	18	view →
THCA	DFS	Tertile	III,IV	0.242	0.766	.009	12	view →
LGG	OS	Tertile	All	0.800	0.900	.009	9	view →
HNSC	OS	Tertile	All	0.161	0.413	.020	9	view →
BRCA	DFS	Tertile	III,IV	0.690	0.418	.019	6	view →
UCEC	OS	Tertile	All	0.824	0.881	.044	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNU2-35P–KICH (DFS)

Open the KICH breakdown →