Across TCGA pan-cancer cohorts, RNU2-28P RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RNU2-28P data layer.
The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher RNU2-28P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU2-28P expression acts as an unfavorable survival marker, although some lineages such as LIHC and KIRP show a favorable association.
PAAD, LGG, and READ are the cancer types where RNU2-28P RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.