RNU2-27P

Across TCGA pan-cancer cohorts, RNU2-27P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RNU2-27P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU2-27P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU2-27P expression acts as an unfavorable survival marker, although some lineages such as UCS and KIRC show a favorable association.

ACC, CESC, and UCS are the cancer types where RNU2-27P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.240	0.666	<.001	99	view →
CESC	DFS	Median	III,IV	0.409	0.842	<.001	64	view →
UCS	DFS	Median	IV	0.952	0.367	.001	56	view →
KIRC	DFS	Median	II,III,IV	0.777	0.529	.002	42	view →
BRCA	DFS	Tertile	III,IV	0.536	0.407	.004	27	view →
LGG	OS	Quartile	All	0.717	0.886	<.001	27	view →
UVM	DFS	Tertile	III,IV	0.259	0.860	.002	18	view →
MESO	DFS	Median	III,IV	0.274	0.464	.002	18	view →
GBM	OS	Median	All	0.538	0.278	<.001	15	view →
LUAD	DFS	Quartile	III,IV	0.556	0.197	.018	15	view →
BLCA	DFS	Quartile	All	0.322	0.604	.007	12	view →
THYM	OS	Tertile	All	1.000	0.910	.023	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RNU2-27P–ACC (DFS)

Open the ACC breakdown →