RNU2-1

Across TCGA pan-cancer cohorts, RNU2-1 RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated RNU2-1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU2-1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU2-1 expression acts as an unfavorable survival marker.

BLCA, HNSC, and ESCA are the cancer types where RNU2-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.111	0.720	<.001	108	view →
HNSC	OS	Tertile	II,III,IV	0.082	0.711	<.001	72	view →
ESCA	DFS	Tertile	II,III,IV	0.099	0.507	<.001	72	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

RNU2-1–BLCA (OS)

Open the BLCA breakdown →