RNU2-1

Q-omics provides the consensus-scored RNU2-1 profile across patient tissues and cancer cell-line models. RNU2-1 expression is associated with patient survival in 3 of 34 cancer types, with the highest sampling consensus in BLCA. Additionally, RNU2-1 RNA expression shows 291 significant gene co-expression associations, with the highest sampling consensus in HNSC. Together, these results highlight BLCA, and HNSC as cancer lineages where RNU2-1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes RNU2-1 survival associations across molecular data types. RNU2-1 RNA expression shows survival associations in the most cancer types (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU2-1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	3	BLCA (108)	view →

This table ranks reproducible RNU2-1 RNA expression–survival associations across cancer types. High RNU2-1 expression shows unfavorable associations in BLCA, ESCA and HNSC. The BLCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BLCA as the clearest survival context for RNU2-1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.111	0.720	<.001	108	view →
ESCA	DFS	Tertile	II,III,IV	0.099	0.507	<.001	72	view →
HNSC	OS	Tertile	II,III,IV	0.082	0.711	<.001	72	view →

Pink = unfavorable, green = favorable. all 3 lineages →

RNU2-1-BLCA (OS)

Explore this curve interactively →