Across TCGA pan-cancer cohorts, RNU105B RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNU105B’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RNU105B RNA is repressed in tumor relative to normal tissue. In most cancer types RNU105B is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KICH and LUAD are the cancer types where RNU105B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU105B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.088	.008	3	view →
LUAD	All	All	+0.151	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: RNU105B RNA expression & survival · all RNU105B data types