Across TCGA pan-cancer cohorts, RNU1-89P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU1-89P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNU1-89P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU1-89P is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, BRCA, and KICH are the cancer types where RNU1-89P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU1-89P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.184	<.001	6	view →
BRCA	Female	All	+0.164	.046	2	view →
KICH	All	All	−0.149	.014	2	view →
LUAD	All	All	+0.293	.046	1	view →
KIRP	All	All	−0.158	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RNU1-89P RNA expression & survival · all RNU1-89P data types