Across TCGA pan-cancer cohorts, RNU1-63P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU1-63P’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNU1-63P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU1-63P is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

THCA, KIRC, and LUSC are the cancer types where RNU1-63P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU1-63P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.099	.015	2	view →
KIRC	All	All	+0.070	.038	2	view →
LUSC	All	II,III,IV	−0.143	.038	1	view →
LIHC	All	II,III,IV	+0.098	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNU1-63P RNA expression & survival · all RNU1-63P data types