Across TCGA pan-cancer cohorts, RNU1-27P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU1-27P data layer.
The strongest signal is observed in thymoma (THYM), where higher RNU1-27P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU1-27P expression acts as an unfavorable survival marker, although some lineages such as LUAD and KIRC show a favorable association.
THYM, READ, and ESCA are the cancer types where RNU1-27P RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.