Across TCGA pan-cancer cohorts, RNU1-27P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU1-27P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNU1-27P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU1-27P is over-expressed in tumor, although a few such as KIRC and UCEC show the opposite, repressed pattern.

KIRC, UCEC, and STAD are the cancer types where RNU1-27P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU1-27P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.097	.009	3	view →
UCEC	All	IV	−0.870	.002	2	view →
STAD	Female	III,IV	+1.640	.005	1	view →
KICH	Male	All	−0.250	.034	1	view →
THCA	Male	All	−0.180	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RNU1-27P RNA expression & survival · all RNU1-27P data types