Across TCGA pan-cancer cohorts, RNU1-21P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNU1-21P’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RNU1-21P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU1-21P is over-expressed in tumor.

COAD and LUAD are the cancer types where RNU1-21P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU1-21P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.259	.026	2	view →
LUAD	All	All	+0.124	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: RNU1-21P RNA expression & survival · all RNU1-21P data types