RNU1-134P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU1-134P RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RNU1-134P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU1-134P RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNU1-134P expression acts as an unfavorable survival marker, although some lineages such as BLCA and HNSC show a favorable association.

BLCA, THCA, and UCEC are the cancer types where RNU1-134P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCAOSMedianAll0.5350.336.001134view →
THCAOSTertileAll0.8660.967<.001114view →
UCECDFSMedianAll0.7750.873<.00198view →
UVMDFSTertileIII,IV0.0340.758<.00175view →
CESCDFSTertileAll0.7500.858.00242view →
KIRCDFSTertileAll0.7560.827.00339view →
COADDFSTertileIV0.1860.655.00434view →
HNSCOSMedianII,III,IV0.8140.692.00133view →
LGGDFSQuartileAll0.6210.776<.00128view →
ACCOSQuartileAll0.6190.838.00123view →
MESODFSTertileII,III,IV0.2460.532.03318view →
ESCAOSTertileAll0.5640.748.01515view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

Exploration