RNPEPL1

Across TCGA cell cohorts, RNPEPL1 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNPEPL1-associated genes across cancer lineages are CRYBB3, LMX1A, and TMEM196. Each is linked with RNPEPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNPEPL1-to-partner and partner-to-RNPEPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYBB3 grouped by RNPEPL1-low versus RNPEPL1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNPEPL1→partner) and Y-score (partner→RNPEPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CRYBB3 →	+0.104	+4.152	<.001	.009	3	1
BLOOD_Leukemia	LMX1A →	+0.172	+4.409	<.001	.005	3	1
BLOOD_Leukemia	TMEM196 →	+0.053	+4.874	<.001	.002	3	1
BLOOD_Leukemia	OR8D4 →	+0.004	+4.539	<.001	.007	3	1
BLOOD_Leukemia	OR6M1 →	+0.016	+4.539	<.001	.007	3	1
BLOOD_Leukemia	GSG1L2 →	+0.043	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

CRYBB3 by RNPEPL1 expression — BLOOD_Leukemia

Explore this box plot interactively →