RNPEP

Across TCGA patient cohorts, RNPEP protein abundance is significantly associated with the RNA expression of many other genes, with 12,682 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RNPEP-associated genes across cancer lineages are ODR4, ADIPOR1, and PEX19. Each is linked with RNPEP in more than 8 cancer types. Because this analysis shows association rather than direction, both RNPEP-to-partner and partner-to-RNPEP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNPEP versus ODR4 in BRCA, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNPEP→partner) and Y-score (partner→RNPEP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ODR4 →	+0.671	+0.425	<.001	<.001	3	8
HNSC	ADIPOR1 →	+0.670	+0.234	.004	<.001	2	9
BRCA	PEX19 →	+0.481	+0.403	<.001	<.001	3	7
BRCA	DENND1B →	+0.946	+0.318	.001	.008	3	7
HNSC	KLHL12 →	+0.741	+0.221	<.001	<.001	2	7
UCEC	RNASEL →	+0.613	+0.228	.003	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,682 associations by consensus.

RNPEP vs ODR4 — BRCA

Explore this scatter interactively →