RNMT

Across TCGA cell cohorts, RNMT mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNMT-associated genes across cancer lineages are FEZF1, UGT2B4, and TGM6. Each is linked with RNMT in more than 1 cancer types. Because this analysis shows association rather than direction, both RNMT-to-partner and partner-to-RNMT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FEZF1 grouped by RNMT-low versus RNMT-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNMT→partner) and Y-score (partner→RNMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FEZF1 →	+0.034	+3.956	<.001	.005	3	1
BLOOD_Leukemia	UGT2B4 →	+0.056	+3.855	<.001	.007	3	1
BLOOD_Leukemia	TGM6 →	+0.018	+4.984	<.001	.002	3	1
BLOOD_Leukemia	GOLGA6C →	+0.057	+3.934	<.001	.005	3	1
BLOOD_Leukemia	OR10T2 →	+0.600	+4.691	.001	<.001	3	1
BLOOD_Leukemia	OR10R2 →	+1.834	+3.551	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

FEZF1 by RNMT expression — BLOOD_Leukemia

Explore this box plot interactively →