RNH1

Across TCGA cell cohorts, RNH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,994 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNH1-associated GO terms across cancer lineages are Actin filament depolymerization, Protein localization to endosome, and Modulation by symbiont of entry into host. Each is linked with RNH1 in more than 13 cancer types. Because this analysis shows association rather than direction, both RNH1-to-partner and partner-to-RNH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament depolymerization grouped by RNH1-low versus RNH1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNH1→partner) and Y-score (partner→RNH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Actin filament depolymerization →	+0.169	+0.872	<.001	<.001	3	14
BONE	Protein localization to endosome →	+0.157	+0.759	.007	.002	2	14
LIVER	Modulation by symbiont of entry into host →	+0.174	+0.775	<.001	.002	3	13
LUNG_NSCLC_LUSC	Negative regulation of Rho protein signal transduction →	+0.170	+0.933	.002	.003	3	13
OESOPHAGUS	Telomere tethering at nuclear periphery →	+0.140	+1.279	<.001	<.001	3	13
OESOPHAGUS	Cellular response to methylglyoxal →	+0.177	+0.706	.002	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,994 associations by consensus.

Actin filament depolymerization by RNH1 expression — SKIN

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