RNFT2

Across TCGA patient cohorts, RNFT2 mutation is significantly associated with the RNA expression of many other genes, with 1,281 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNFT2-associated genes across cancer lineages are ATP2B2-IT1, RPS29P25, and NBPF5P. Each is linked with RNFT2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RNFT2-to-partner and partner-to-RNFT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP2B2-IT1 grouped by RNFT2-low versus RNFT2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNFT2→partner) and Y-score (partner→RNFT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP2B2-IT1 →	+0.035	+3.167	.004	.005	3	3
SKCM	RPS29P25 →	+0.079	+5.228	<.001	.001	3	2
SKCM	NBPF5P →	+0.044	+3.042	.003	.001	3	2
LUAD	HSPD1P18 →	+0.209	+5.217	<.001	.007	3	2
HNSC	MIR887 →	+0.773	+5.368	<.001	.005	3	2
UCEC	EME1 →	+0.530	+3.212	.007	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,281 associations by consensus.

ATP2B2-IT1 by RNFT2 expression — UCEC

Explore this box plot interactively →