RNFT2

Across TCGA pan-cancer cohorts, RNFT2 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated RNFT2 data layer compared with 4 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNFT2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNFT2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SCLC show a favorable association.

KICH, LIHC, and HNSC are the cancer types where RNFT2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Quartile	II,III,IV	0.336	1.000	.001	88	view →
LIHC	DFS	Median	All	0.442	0.636	<.001	88	view →
HNSC	DFS	Median	IV	0.731	0.549	<.001	53	view →
MESO	OS	Quartile	All	0.265	0.505	.003	50	view →
SCLC	DFS	Median	II,III,IV	0.753	0.429	.008	29	view →
LUAD	DFS	Quartile	All	0.712	0.884	<.001	28	view →
LUSC	DFS	Tertile	III,IV	0.186	0.897	.002	19	view →
SKCM	DFS	Median	III,IV	0.362	0.692	<.001	17	view →
PRAD	DFS	Quartile	All	0.857	0.961	<.001	16	view →
KIRP	DFS	Median	IV	0.038	0.527	.010	15	view →
PAAD	DFS	Tertile	All	0.416	0.196	.020	12	view →
LGG	OS	Tertile	All	0.570	0.378	.007	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

RNFT2–KICH (OS)

Open the KICH breakdown →