RNFT2

Across TCGA cell cohorts, RNFT2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNFT2-associated genes across cancer lineages are PRAC1, RBMY1J, and OR5V1. Each is linked with RNFT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNFT2-to-partner and partner-to-RNFT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAC1 grouped by RNFT2-low versus RNFT2-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNFT2→partner) and Y-score (partner→RNFT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PRAC1 →	+4.617	+5.029	<.001	.006	3	1
SKIN	RBMY1J →	+0.006	+4.977	<.001	.007	3	1
SKIN	OR5V1 →	+0.016	+4.977	<.001	.007	3	1
LARGE_INTESTINE	HMX3 →	+0.492	+3.531	.002	.007	3	1
LARGE_INTESTINE	EFHC2 →	+0.457	+3.555	.001	.003	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

PRAC1 by RNFT2 expression — LUNG_SCLC

Explore this box plot interactively →