RNFT1-DT

Across TCGA pan-cancer cohorts, RNFT1-DT RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RNFT1-DT data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RNFT1-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNFT1-DT expression acts as an unfavorable survival marker, although some lineages such as KIRP and LUAD show a favorable association.

KIRP, LUAD, and SKCM are the cancer types where RNFT1-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.754	0.605	<.001	70	view →
LUAD	OS	Tertile	II,III,IV	0.837	0.544	<.001	49	view →
SKCM	OS	Median	All	0.263	0.492	<.001	48	view →
KICH	OS	Tertile	All	0.557	1.000	.003	34	view →
COAD	OS	Quartile	II,III,IV	0.934	0.766	.015	20	view →
MESO	DFS	Quartile	All	0.306	0.765	.026	18	view →
STAD	DFS	Median	IV	0.130	0.516	.012	12	view →
LGG	DFS	Median	All	0.775	0.872	.007	10	view →
SARC	OS	Quartile	All	0.816	0.606	.018	10	view →
LIHC	OS	Tertile	All	0.840	0.653	.011	7	view →
UVM	DFS	Median	II,III,IV	0.732	0.417	.009	6	view →
CHOL	OS	Median	All	0.876	0.182	.003	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

RNFT1-DT–KIRP (OS)

Open the KIRP breakdown →