RNFT1-DT

Across TCGA pan-cancer cohorts, RNFT1-DT RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RNFT1-DT’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RNFT1-DT RNA is repressed in tumor relative to normal tissue. In most cancer types RNFT1-DT is over-expressed in tumor, although a few such as HNSC and THCA show the opposite, repressed pattern.

HNSC, THCA, and KIRC are the cancer types where RNFT1-DT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNFT1-DT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	−0.183	<.001	10	view →
THCA	Male	IV	−0.520	<.001	9	view →
KIRC	Female	All	−0.269	<.001	9	view →
KIRP	All	All	−0.206	.001	8	view →
COAD	Female	II,III,IV	−0.301	<.001	6	view →
KICH	All	All	−0.303	.001	5	view →
READ	All	All	−0.259	.005	2	view →
BLCA	All	All	+0.230	.040	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RNFT1-DT–HNSC

Open the HNSC breakdown →