RNF8

Across TCGA patient cohorts, RNF8 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,358 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RNF8-associated proteins across cancer lineages are CMTR1, WRNIP1, and XPO5. Each is linked with RNF8 in more than 5 cancer types. Because this analysis shows association rather than direction, both RNF8-to-partner and partner-to-RNF8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF8 versus CMTR1 in LSCC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF8→partner) and Y-score (partner→RNF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CMTR1 →	+0.297	+0.349	<.001	<.001	3	6
LSCC	WRNIP1 →	+0.405	+0.508	<.001	<.001	3	6
LSCC	XPO5 →	+0.646	+0.612	<.001	<.001	3	6
LUAD	SRPK1 →	+0.387	+0.413	<.001	<.001	3	5
LSCC	NONO →	+0.170	+0.486	<.001	<.001	3	5
LSCC	RNF8_S157 →	+0.541	+0.595	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,358 associations by consensus.

RNF8 vs CMTR1 — LSCC

Explore this scatter interactively →