RNF32

Across TCGA cell cohorts, RNF32 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF32-associated genes across cancer lineages are GOLGA6L2, OR6J1, and SPINK14. Each is linked with RNF32 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF32-to-partner and partner-to-RNF32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GOLGA6L2 grouped by RNF32-low versus RNF32-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF32→partner) and Y-score (partner→RNF32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GOLGA6L2 →	+0.010	+5.121	.009	<.001	3	1
BLOOD_Leukemia	OR6J1 →	+0.046	+4.234	<.001	.003	3	1
LARGE_INTESTINE	SPINK14 →	+0.182	+4.977	<.001	.007	3	1
OVARY	TBC1D3H →	+0.486	+5.196	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

GOLGA6L2 by RNF32 expression — BLOOD_Leukemia

Explore this box plot interactively →