RNF31

Across TCGA cell cohorts, RNF31 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,405 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF31-associated GO terms across cancer lineages are Protein linear polyubiquitination, miRNA processing, and Post-transcriptional gene silencing. Each is linked with RNF31 in more than 19 cancer types. Because this analysis shows association rather than direction, both RNF31-to-partner and partner-to-RNF31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein linear polyubiquitination grouped by RNF31-low versus RNF31-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF31→partner) and Y-score (partner→RNF31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein linear polyubiquitination →	+0.200	+1.043	<.001	<.001	3	20
OESOPHAGUS	miRNA processing →	+0.096	+0.811	.006	.008	3	15
STOMACH	Post-transcriptional gene silencing →	+0.097	+0.549	.007	.001	2	15
OESOPHAGUS	Regulatory ncRNA-mediated gene silencing →	+0.085	+0.723	.002	.006	3	13
URINARY_TRACT	Negative regulation of RNA splicing →	+0.114	+1.171	<.001	.006	3	13
UPPER_AERODIGESTIVE_TRACT	Leukotriene signaling pathway →	+1.338	+1.073	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,405 associations by consensus.

Protein linear polyubiquitination by RNF31 expression — PANCREAS

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