RNF25

Across TCGA patient cohorts, RNF25 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,616 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RNF25-associated proteins across cancer lineages are MAP2, SH3BP4, and FARSB. Each is linked with RNF25 in more than 4 cancer types. Because this analysis shows association rather than direction, both RNF25-to-partner and partner-to-RNF25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF25 versus MAP2 in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF25→partner) and Y-score (partner→RNF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MAP2 →	+0.856	+0.492	<.001	<.001	3	4
CCRCC	SH3BP4 →	+0.440	+0.326	<.001	<.001	3	4
PDAC	FARSB →	+0.236	+0.243	.003	.002	2	5
PDAC	FNDC3A_S203 →	-0.332	-0.220	.003	.001	3	4
LUAD	PRDX4 →	-0.372	-0.327	.001	<.001	3	4
BRCA	TP53BP1 →	+0.243	+0.427	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,616 associations by consensus.

RNF25 vs MAP2 — LSCC

Explore this scatter interactively →