RNF25

Across TCGA patient cohorts, RNF25 protein abundance is significantly associated with the RNA expression of many other genes, with 3,649 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RNF25-associated genes across cancer lineages are ARPC2, RPE, and CUL3. Each is linked with RNF25 in more than 5 cancer types. Because this analysis shows association rather than direction, both RNF25-to-partner and partner-to-RNF25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF25 versus ARPC2 in OV, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF25→partner) and Y-score (partner→RNF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ARPC2 →	+0.657	+0.412	<.001	<.001	3	6
OV	RPE →	+0.645	+0.435	<.001	<.001	3	5
OV	CUL3 →	+0.427	+0.277	<.001	.003	3	5
LSCC	XRCC5 →	+0.527	+0.251	<.001	<.001	3	5
BRCA	MRPL44 →	+0.380	+0.204	<.001	<.001	3	4
LSCC	CNOT9 →	+0.457	+0.261	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,649 associations by consensus.

RNF25 vs ARPC2 — OV

Explore this scatter interactively →