RNF25

Across TCGA patient cohorts, RNF25 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF25-associated genes across cancer lineages are Class-switched memory B-cells, aDC, and lymphatic Endothelial cells. Each is linked with RNF25 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF25-to-partner and partner-to-RNF25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Class-switched memory B-cells grouped by RNF25-low versus RNF25-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF25→partner) and Y-score (partner→RNF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Class-switched memory B-cells →	+0.075	+3.178	.009	.023	3	1
UCEC	aDC →	+0.099	+2.839	.005	.034	3	1
UCEC	lymphatic Endothelial cells →	-0.024	-3.531	.034	.003	2	1
UCEC	Endothelial cells →	-0.044	-2.416	.017	.021	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Class-switched memory B-cells by RNF25 expression — COAD

Explore this box plot interactively →