RNF224

Across TCGA cell cohorts, RNF224 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,245 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RNF224-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Cilium-dependent cell motility, and Cilium movement involved in cell motility. Each is linked with RNF224 in more than 13 cancer types. Because this analysis shows association rather than direction, both RNF224-to-partner and partner-to-RNF224 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by RNF224-low versus RNF224-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF224→partner) and Y-score (partner→RNF224) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.148	-1.487	<.001	<.001	3	14
OESOPHAGUS	Cilium-dependent cell motility →	-0.148	-1.487	<.001	<.001	3	14
OESOPHAGUS	Cilium movement involved in cell motility →	-0.160	-1.450	<.001	<.001	3	14
BONE	Regulation of myoblast fusion →	+0.112	+0.733	<.001	<.001	3	13
OVARY	Negative regulation of myoblast fusion →	+0.118	+0.820	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.134	+0.575	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,245 associations by consensus.

Cilium or flagellum-dependent cell motility by RNF224 expression — OESOPHAGUS

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