Across TCGA patient cohorts, RNF220 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,755 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RNF220-associated proteins across cancer lineages are SUPT16H, DEK, and PPIH. Each is linked with RNF220 in more than 4 cancer types. Because this analysis shows association rather than direction, both RNF220-to-partner and partner-to-RNF220 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF220→partner) and Y-score (partner→RNF220) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SUPT16H →	+0.311	+0.302	.004	.002	3	5
OV	DEK →	+0.428	+0.308	.001	.003	3	5
OV	PPIH →	+0.319	+0.307	.003	.005	3	5
BRCA	SMC3 →	+0.337	+0.507	<.001	<.001	3	4
BRCA	SRA1 →	-0.383	-0.578	<.001	<.001	3	4
LUAD	SRP68 →	-0.213	-0.292	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,755 associations by consensus.

Exploration

RNF220 survival (RNA) · tumor vs normal (RNA) · all RNF220 data types