RNF217-AS1

Across TCGA pan-cancer cohorts, RNF217-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RNF217-AS1 data layer compared with 2 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNF217-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNF217-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and SKCM show a favorable association.

BLCA, UCS, and SKCM are the cancer types where RNF217-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.521	0.693	<.001	101	view →
UCS	DFS	Tertile	II,III,IV	0.568	0.181	.005	48	view →
SKCM	OS	Tertile	IV	0.855	0.307	.002	39	view →
LGG	OS	Tertile	All	0.879	0.749	<.001	33	view →
THCA	DFS	Median	All	0.938	0.690	.001	24	view →
COAD	DFS	Median	IV	0.338	0.608	.002	16	view →
READ	DFS	Tertile	II,III,IV	0.429	0.895	.002	16	view →
OV	OS	Median	All	0.882	0.799	.001	14	view →
MESO	OS	Median	All	0.294	0.674	.016	13	view →
HNSC	OS	Quartile	All	0.456	0.796	.001	12	view →
KIRP	DFS	Quartile	All	1.000	0.576	.007	10	view →
LIHC	OS	Tertile	II,III,IV	0.817	0.639	.018	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RNF217-AS1–BLCA (OS)

Open the BLCA breakdown →