Across TCGA patient cohorts, RNF216P1 mutation is significantly associated with the RNA expression of many other genes, with 318 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF216P1-associated genes across cancer lineages are PIGPP3, OR7E53P, and MTND2P14. Each is linked with RNF216P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF216P1-to-partner and partner-to-RNF216P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF216P1→partner) and Y-score (partner→RNF216P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PIGPP3 →	+0.345	+5.017	<.001	.009	3	2
SKCM	OR7E53P →	+0.121	+5.292	<.001	.006	3	1
SKCM	MTND2P14 →	+0.147	+6.993	<.001	<.001	3	1
UCEC	TEX30 →	+0.875	+3.470	<.001	.002	3	1
UCEC	CC2D1B →	+0.380	+3.595	.001	.001	3	1
UCEC	PHKG2 →	+0.456	+3.191	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 318 associations by consensus.

Exploration

RNF216P1 survival (RNA) · tumor vs normal (RNA) · all RNF216P1 data types