RNF215

Across TCGA cell cohorts, RNF215 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF215-associated genes across cancer lineages are TAAR1, SPANXN4, and KRTAP21-2. Each is linked with RNF215 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF215-to-partner and partner-to-RNF215 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR1 grouped by RNF215-low versus RNF215-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF215→partner) and Y-score (partner→RNF215) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TAAR1 →	+0.022	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	SPANXN4 →	+0.107	+4.867	<.001	.009	3	1
BLOOD_Leukemia	KRTAP21-2 →	+0.062	+4.539	.001	.007	3	1
BLOOD_Leukemia	FAM24A →	+0.061	+4.969	<.001	.003	3	1
BLOOD_Leukemia	DEFB131B →	+0.238	+4.969	<.001	.003	3	1
BLOOD_Leukemia	USP17L13 →	+0.004	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

TAAR1 by RNF215 expression — BLOOD_Lymphoma

Explore this box plot interactively →