RNF214

Across TCGA cell cohorts, RNF214 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,405 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNF214-associated GO terms across cancer lineages are Ether catabolic process, Positive regulation of TORC2 signaling, and Glycerol ether catabolic process. Each is linked with RNF214 in more than 14 cancer types. Because this analysis shows association rather than direction, both RNF214-to-partner and partner-to-RNF214 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ether catabolic process grouped by RNF214-low versus RNF214-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF214→partner) and Y-score (partner→RNF214) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Ether catabolic process →	+0.217	+0.715	<.001	<.001	3	15
KIDNEY	Positive regulation of TORC2 signaling →	+0.108	+0.894	<.001	<.001	3	15
BREAST	Glycerol ether catabolic process →	+0.217	+0.715	<.001	<.001	3	15
BREAST	Platelet activating factor catabolic process →	+0.217	+0.715	<.001	<.001	3	15
LUNG_SCLC	Negative regulation of gene expression, epigenetic →	+0.068	+0.565	<.001	<.001	3	14
SOFT_TISSUE	Regulation of chromosome organization →	+0.074	+0.475	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,405 associations by consensus.

Ether catabolic process by RNF214 expression — BREAST

Explore this box plot interactively →