RNF207

Across TCGA cell cohorts, RNF207 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,389 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RNF207-associated GO terms across cancer lineages are Positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential, Positive regulation of membrane repolarization during cardiac muscle cell action potential, and Regulation of membrane repolarization during ventricular cardiac muscle cell action potential. Each is linked with RNF207 in more than 19 cancer types. Because this analysis shows association rather than direction, both RNF207-to-partner and partner-to-RNF207 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential grouped by RNF207-low versus RNF207-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF207→partner) and Y-score (partner→RNF207) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential →	+1.503	+2.348	<.001	<.001	3	20
LIVER	Positive regulation of membrane repolarization during cardiac muscle cell action potential →	+1.503	+2.348	<.001	<.001	3	20
BLOOD_Myeloma	Regulation of membrane repolarization during ventricular cardiac muscle cell action potential →	+1.762	+2.353	<.001	<.001	3	19
KIDNEY	Response to epidermal growth factor →	+0.101	+1.391	.003	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.112	-1.599	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.109	-1.515	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,389 associations by consensus.

Positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential by RNF207 expression — LIVER

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