RNF207

Across TCGA pan-cancer cohorts, RNF207 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of RNF207’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RNF207 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNF207 is over-expressed in tumor, although a few such as KICH and PRAD show the opposite, repressed pattern.

LUAD, STAD, and LIHC are the cancer types where RNF207 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNF207 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	II,III,IV	+0.658	<.001	9	view →
STAD	All	II,III,IV	+1.031	<.001	8	view →
LIHC	Female	II,III,IV	+0.978	<.001	8	view →
COAD	Female	All	+0.806	<.001	6	view →
BLCA	All	All	+0.794	.002	6	view →
PAAD	Female	All	+1.640	.030	4	view →
LUSC	Male	All	+0.625	<.001	4	view →
KICH	All	All	−0.590	<.001	4	view →
CHOL	All	All	+1.581	<.001	3	view →
KIRP	All	IV	+1.497	.025	3	view →
KIRC	Male	IV	+0.449	.047	3	view →
PRAD	All	All	−0.478	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

RNF207–LUAD

Open the LUAD breakdown →