RNF207

Across TCGA cell cohorts, RNF207 mutation is significantly associated with the RNA expression of many other genes, with 216 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNF207-associated genes across cancer lineages are DCD, ADIPOQ, and CGB2. Each is linked with RNF207 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF207-to-partner and partner-to-RNF207 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCD grouped by RNF207-low versus RNF207-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF207→partner) and Y-score (partner→RNF207) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	DCD →	+0.068	+4.977	.001	.007	3	1
LUNG_NSCLC_LUAD	ADIPOQ →	+0.022	+5.228	<.001	.005	3	1
BLOOD_Leukemia	CGB2 →	+1.303	+4.234	<.001	.003	3	1
BLOOD_Leukemia	CRYGD →	+2.159	+4.234	<.001	.003	3	1
BLOOD_Leukemia	OR4K2 →	+0.025	+4.384	<.001	.006	3	1
BLOOD_Leukemia	MBD3L1 →	+0.013	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 216 associations by consensus.

DCD by RNF207 expression — SKIN

Explore this box plot interactively →