RNF19A

Across TCGA patient cohorts, RNF19A protein abundance is significantly associated with the RNA expression of many other genes, with 4,321 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible RNF19A-associated genes across cancer lineages are PLCL2, AFF2, and AZIN1. Each is linked with RNF19A in more than 2 cancer types. Because this analysis shows association rather than direction, both RNF19A-to-partner and partner-to-RNF19A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF19A versus PLCL2 in OV, with a Pearson correlation of -0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF19A→partner) and Y-score (partner→RNF19A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PLCL2 →	-0.722	-0.550	.008	.007	2	3
OV	AFF2 →	-2.472	-0.550	<.001	.007	3	2
BRCA	AZIN1 →	+0.855	+0.579	.002	.007	3	2
BRCA	ATP6V1C1 →	+0.919	+0.625	.001	.002	3	2
BRCA	HNRNPF →	+0.697	+0.605	.002	.003	3	2
LSCC	S100A14 →	+1.942	+0.699	.006	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,321 associations by consensus.

RNF19A vs PLCL2 — OV

Explore this scatter interactively →