RNF19A

Across TCGA patient cohorts, RNF19A mutation is significantly associated with the RNA expression of many other genes, with 2,316 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF19A-associated genes across cancer lineages are RNU6-380P, TRBV10-2, and LINC02641. Each is linked with RNF19A in more than 2 cancer types. Because this analysis shows association rather than direction, both RNF19A-to-partner and partner-to-RNF19A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-380P grouped by RNF19A-low versus RNF19A-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF19A→partner) and Y-score (partner→RNF19A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-380P →	+0.118	+4.247	<.001	.007	3	3
UCEC	TRBV10-2 →	+0.395	+1.480	<.001	.008	3	3
UCEC	LINC02641 →	+0.111	+1.546	.009	.005	3	3
BRCA	SRIP2 →	+0.294	+4.683	<.001	.007	3	2
CESC	MIR30C1 →	+0.320	+3.507	<.001	.005	3	2
CESC	PPIAL4F →	+0.057	+3.063	.005	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,316 associations by consensus.

RNU6-380P by RNF19A expression — CESC

Explore this box plot interactively →