RNF17

Across TCGA patient cohorts, RNF17 protein abundance is significantly associated with the RNA expression of many other genes, with 1,850 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RNF17-associated genes across cancer lineages are DPY19L1, PMCHL2, and LRRN4CL. Each is linked with RNF17 in more than 3 cancer types. Because this analysis shows association rather than direction, both RNF17-to-partner and partner-to-RNF17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF17 versus DPY19L1 in BRCA, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF17→partner) and Y-score (partner→RNF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DPY19L1 →	+0.893	+0.786	.008	<.001	3	4
OV	PMCHL2 →	-0.647	-0.427	.005	<.001	3	2
GBM	LRRN4CL →	+1.097	+0.665	<.001	<.001	3	2
OV	ADAMTS9-AS1 →	+0.577	+0.478	.002	.003	3	2
BRCA	COL16A1 →	+1.306	+0.629	.004	.004	3	2
HNSC	NECTIN1 →	-1.072	-0.382	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,850 associations by consensus.

RNF17 vs DPY19L1 — BRCA

Explore this scatter interactively →