RNF169

Across TCGA patient cohorts, RNF169 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF169-associated genes across cancer lineages are Endothelial cells, Erythrocytes, and lymphatic Endothelial cells. Each is linked with RNF169 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF169-to-partner and partner-to-RNF169 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by RNF169-low versus RNF169-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF169→partner) and Y-score (partner→RNF169) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Endothelial cells →	-0.040	-2.991	.029	.036	3	1
UCEC	Erythrocytes →	+0.025	+2.879	.034	.033	3	1
UCEC	lymphatic Endothelial cells →	-0.024	-3.129	.039	.019	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Endothelial cells by RNF169 expression — UCEC

Explore this box plot interactively →