RNF167

Across TCGA pan-cancer cohorts, RNF167 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RNF167 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNF167 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RNF167 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

HNSC, PDAC, and LUAD are the cancer types where RNF167 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	III,IV	1.000	0.344	.009	20	view →
PDAC	DFS	Median	All	0.286	0.543	.011	13	view →
LUAD	DFS	Quartile	III,IV	0.527	0.996	.006	10	view →
CCRCC	DFS	Quartile	All	1.000	0.246	.011	9	view →
OV	DFS	Quartile	All	0.583	0.942	.035	8	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RNF167–HNSC (OS)

Open the HNSC breakdown →