RNF157-AS1

Across TCGA pan-cancer cohorts, RNF157-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RNF157-AS1 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher RNF157-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNF157-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG and PAAD show a favorable association.

LGG, PAAD, and BRCA are the cancer types where RNF157-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Tertile	All	0.492	0.325	<.001	37	view →
PAAD	OS	Quartile	All	0.607	0.284	.004	26	view →
BRCA	OS	Median	II,III,IV	0.970	0.943	.005	24	view →
SKCM	OS	Tertile	III,IV	0.547	0.236	.001	22	view →
CHOL	DFS	Tertile	All	0.792	0.116	.006	18	view →
CESC	OS	Tertile	III,IV	0.844	0.519	.016	18	view →
UVM	OS	Median	III,IV	0.607	1.000	.009	16	view →
KIRP	DFS	Quartile	All	1.000	0.793	.019	16	view →
LIHC	DFS	Median	All	0.403	0.644	.001	12	view →
THYM	DFS	Median	II,III,IV	0.688	0.950	.006	10	view →
KICH	OS	Tertile	All	0.744	1.000	.032	9	view →
READ	DFS	Tertile	All	0.291	0.795	.002	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RNF157-AS1–LGG (DFS)

Open the LGG breakdown →