RNF152

Across TCGA patient cohorts, RNF152 mutation is significantly associated with the RNA expression of many other genes, with 899 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF152-associated genes across cancer lineages are MIR7702, CORT, and CRYBB2. Each is linked with RNF152 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF152-to-partner and partner-to-RNF152 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7702 grouped by RNF152-low versus RNF152-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF152→partner) and Y-score (partner→RNF152) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7702 →	+0.245	+4.360	<.001	.004	3	2
SKCM	CORT →	+0.194	+1.906	.006	.001	3	2
UCEC	CRYBB2 →	+0.898	+2.700	.001	.006	3	2
CESC	RN7SL492P →	+0.229	+5.669	<.001	.003	3	2
LUAD	SULT1D1P →	+0.112	+2.914	.006	.006	3	2
UCEC	MEX3D →	+0.678	+3.346	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 899 associations by consensus.

MIR7702 by RNF152 expression — UCEC

Explore this box plot interactively →