RNF152

Across TCGA pan-cancer cohorts, RNF152 RNA is linked to patient survival in 29 of 34 cancer types, making it the most broadly survival-associated RNF152 data layer compared with 3 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNF152 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNF152 expression acts as an unfavorable survival marker, although some lineages such as KIRC and ESCA show a favorable association.

KIRC, UVM, and ACC are the cancer types where RNF152 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.726	0.548	<.001	160	view →
UVM	DFS	Tertile	II,III,IV	0.297	0.827	<.001	92	view →
ACC	DFS	Median	All	0.213	0.680	<.001	72	view →
STAD	OS	Quartile	All	0.338	0.531	.015	33	view →
ESCA	OS	Median	All	0.789	0.624	.012	18	view →
CESC	DFS	Median	All	0.864	0.776	.018	16	view →
GBM	OS	Tertile	All	0.629	0.294	.005	15	view →
SKCM	DFS	Quartile	III,IV	0.415	0.657	.003	13	view →
UCS	DFS	Tertile	IV	0.956	0.510	.024	12	view →
THCA	OS	Quartile	All	0.921	1.000	.016	10	view →
PRAD	DFS	Median	All	0.848	0.720	.027	10	view →
PAAD	OS	Tertile	All	0.485	0.710	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 29 lineages.

RNF152–KIRC (OS)

Open the KIRC breakdown →