RNF152

Across TCGA cell cohorts, RNF152 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,561 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF152-associated GO terms across cancer lineages are Positive regulation of synapse structural plasticity, Regulation of G1/S transition of mitotic cell cycle, and Positive regulation of hydrolase activity. Each is linked with RNF152 in more than 7 cancer types. Because this analysis shows association rather than direction, both RNF152-to-partner and partner-to-RNF152 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of synapse structural plasticity grouped by RNF152-low versus RNF152-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF152→partner) and Y-score (partner→RNF152) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of synapse structural plasticity →	-0.696	-1.086	<.001	<.001	3	8
SOFT_TISSUE	Regulation of G1/S transition of mitotic cell cycle →	+0.046	+1.113	.005	.003	3	7
OVARY	Positive regulation of hydrolase activity →	+0.038	+1.057	.006	.004	3	7
BREAST	Proteasome core complex assembly →	-0.125	-1.097	<.001	.002	3	7
URINARY_TRACT	Cellular response to reactive nitrogen species →	-0.123	-1.196	.005	.003	3	6
SOFT_TISSUE	Negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway →	+0.069	+0.952	.002	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,561 associations by consensus.

Positive regulation of synapse structural plasticity by RNF152 expression — BREAST

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