RNF146

Across TCGA cell cohorts, RNF146 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,835 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF146-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Macroautophagy. Each is linked with RNF146 in more than 17 cancer types. Because this analysis shows association rather than direction, both RNF146-to-partner and partner-to-RNF146 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by RNF146-low versus RNF146-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF146→partner) and Y-score (partner→RNF146) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Process utilizing autophagic mechanism →	+0.095	+1.242	<.001	<.001	3	18
STOMACH	Autophagy →	+0.095	+1.242	<.001	<.001	3	18
STOMACH	Macroautophagy →	+0.092	+1.092	<.001	<.001	2	17
STOMACH	Golgi vesicle transport →	+0.074	+1.337	<.001	<.001	3	16
BONE	Vesicle-mediated transport to the plasma membrane →	+0.079	+0.709	.002	.003	3	16
BLOOD_Myeloma	Autophagosome organization →	+0.073	+1.007	<.001	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,835 associations by consensus.

Process utilizing autophagic mechanism by RNF146 expression — STOMACH

Explore this box plot interactively →