RNF145

Across TCGA cell cohorts, RNF145 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,343 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RNF145-associated GO terms across cancer lineages are DNA alkylation repair, Negative regulation of post-translational protein modification, and Regulation of metaphase/anaphase transition of cell cycle. Each is linked with RNF145 in more than 10 cancer types. Because this analysis shows association rather than direction, both RNF145-to-partner and partner-to-RNF145 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA alkylation repair grouped by RNF145-low versus RNF145-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF145→partner) and Y-score (partner→RNF145) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	DNA alkylation repair →	+0.110	+0.831	<.001	.001	2	11
BLOOD_Lymphoma	Negative regulation of post-translational protein modification →	+0.070	+0.792	<.001	<.001	3	10
PANCREAS	Regulation of metaphase/anaphase transition of cell cycle →	+0.098	+0.773	.002	.007	3	10
PANCREAS	Protein localization to nucleus →	+0.055	+1.047	<.001	<.001	3	10
LIVER	Negative regulation of organelle assembly →	+0.062	+1.215	.001	.002	2	11
CNS	Golgi vesicle transport →	+0.049	+0.726	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,343 associations by consensus.

DNA alkylation repair by RNF145 expression — STOMACH

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